The TICAM2 Antibody FITC-Conjugated from MyBioSource.com is a Rabbit Polyclonal antibody to TICAM2. This antibody recognizes Human, Mouse, and Rat antigen. The TICAM2 Antibody FITC-Conjugated has been validated for the following applications: Dot Blot, ELISA, and Western Blot.
Description
FITC-Conjugated TRIF-related adapter molecule Antibody
Functions as sorting adapter in LPS-TLR4 signaling to regulate the MYD88-independent pathway during the innate immune response to LPS. Physically bridges TLR4 and TICAM1 and functionally transmits LPS-TRL4 signal to TICAM1; signaling is proposed to occur in early endosomes after endocytosis of TLR4. May also be involved in IL1-triggered NF-kappa-B activation, functioning upstream of IRAK1, IRAK2, TRAF6, and IKBKB; however, reports are controversial. Involved in IL-18 signaling and is proposed to function as a sorting adaptor for MYD88 in IL-18 signaling during adaptive immune response